PE/Cyanine5 Anti-Human CD197/CCR7 Antibody[G043H7]
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| 商品名称 | PE/Cyanine5 Anti-Human CD197/CCR7 Antibody[G043H7] |
|---|---|
| 品牌 | Elabscience |
| 货号 | E-AB-F1159G |
| 应用性 | FCM |
| 亚型 | Mouse IgG2a, κ |
| 宿主 | Mouse |
| Alternate Names | EBI1EVI1, CCR-7, CDw197, CMKBR7 |
|---|---|
| Cellular Localization | Membrane |
| Clone No | G043H7 |
| Isotype | Mouse IgG2a, κ |
| Leadtime | 咨询 |
| Background | CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naïve T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis. |
| Abbre | CD197 |
| Swissprot | P32248 |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype Control | PE/Cyanine5 Mouse IgG2a, κ Isotype Control[C1.18.4] |
| Applications | FCM |
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | PE/Cyanine 5 |
| Conjugation Information | PE/Cyanine5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping | 冰袋 |
| Gene ID | 1236 |
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